Version June 2024
| Treatment | Efficacy for improving gas exchange in HPS |
| Physically occlude IPVDs | |
| Spring coil embolization | Modest if technically possible |
| Oppose circulating vasodilators | |
| Octreotide (somatostatin analog) | Variable |
| Nitric oxide synthase inhibitors | Variable |
| Indomethacin | Poor |
| Improve V/Q matching | |
| Almitrine bismesylate | Slight |
| Treat underlying liver disease | |
| Chemotherapy and corticosteroids | Helpful in one patient |
| Liver transplantation | Moderately good but variable response |
| Treat portal hypertension | |
| TIPS | Variable |
| Other (miscellaneous) | |
| Methylene blue | Variable in the few patients described |
| Allium sativum (garlic) | Variable |
| Propranolol | None |
| Plasma exchange | None |
| Sympathomimetics | None |
| Aspirin | |
| Pentoxifylline | |
| Antibiotics | |
| Mycophenolate mofetil | |
| Sorafenib (tyrosine kinase inhibitor) | None |
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