Cellular interactions in the pathogenesis of scleroderma
Cellular interactions in the pathogenesis of scleroderma
Schematic representation of the cellular components implicated in the pathogenesis of scleroderma: the vascular endothelial cells, lymphocytes, and fibroblasts. Interplay between these factors, and between the fibroblasts and noncellular components of the extracellular matrix are likely to play an important role.