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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Factors contributing to fatal and near-fatal anaphylactic reactions to SCIT injections

Factors contributing to fatal and near-fatal anaphylactic reactions to SCIT injections
  Fatal reactions[1,2] Near-fatal reactions[3]
(n = 34*) (n = 68)
1. Uncontrolled asthma 62% 10%
2. Prior systemic reaction 53% 9%
3. Pollen season 47% 46%
4. Epinephrine delayed or not given 43% 6%
5. Reaction in allergist's office 59% 93%
6. Dosing/administration errors (3 of 17 given IM) 35% 25%
7. None reported 17% –
8. Inadequate waiting period 12% 3%
9. Home administration 9% 0%
10. Beta-blockers/ACE inhibitors 2% each 3%/1.5%
SCIT: subcutaneous immunotherapy; IM: intramuscularly; ACE: angiotensin-converting enzyme.
* Data combined from two SCIT fatality studies[1,2].
¶ Reference [2] only.
Data from:
  1. Reid MJ, et al. Survey of fatalities from skin testing and immunotherapy 1985 to 1989. J Allergy Clin Immunol 1993; 92:6.
  2. Bernstein DI, et al. Twelve-year survey of fatal reactions to allergen injections and skin testing: 1990 to 2001. J Allergy Clin Immunol 2004; 113:1129.
  3. Amin HS, Liss GM, Bernstein DI. Evaluation of near-fatal reactions to allergen immunotherapy injections. J Allergy Clin Immunol 2006; 117:169.
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