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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Hormonal changes during adrenarche

Hormonal changes during adrenarche
Changing pattern of adrenal steroidogenic response to adrenocorticotropic hormone with maturation. Shown are plasma steroid levels before (basal, 8:00 AM after dexamethasone 1 mg/m2 given 8 hours before) and the rise (Δ) 30 minutes after cosyntropin (ACTH) administration (10 mcg/m2) in healthy prepubertal children, children with premature adrenarche, and follicular-phase adult women. Note that 17-hydroxypregnenolone (17PREG) and dehydroepiandrosterone (DHEA) responses of children with premature adrenarche are intermediate between prepubertal and adult responses.
These changes underlie the characteristic maturational rise in serum DHEA sulfate (DHEAS). DHEAS mean norms (not shown in figure) are 11 mcg/dL in prepubertal girls, 105 mcg/dL in girls with premature adrenarche, and 208 mcg/dL in adult follicular-phase females.
17PROG: 17-hydroxyprogesterone; ADNE: androstenedione; CMPD S: compound S (11-deoxycortisol); CORT: cortisol.
From: Rosenfield RL, Cooke DW, Radovick S. Puberty and its disorders in the female. In: Pediatric Endocrinology, 3rd Edition, Sperling M (Ed). Elsevier, Philadelphia, 2008. Illustration used with the permission of Elsevier Inc. All rights reserved.
Data from: Rich BH, Rosenfield RL, Lucky AW, Helke JC, Otto P. Adrenarche: changing adrenal response to adrenocorticotropin. J Clin Endocrinol Metab. 1981;52:1129-34.
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