Heparin-adjusted nomogram for stroke

Initial dosing for continuous intravenous heparin infusion
Weight (kg)		Initial infusion (U/hour)
<50		500
50 to 59		600
60 to 69		700
70 to 79		800
80 to 89		900
90 to 99		1000
100 to 109		1100
110 to 119		1200
>119		1400
Heparin adjustment based upon aPTT drawn six hours after initiation of therapy
aPTT (seconds)	Stop infusion	Rate change	Repeat aPTT
<40	No	Increase by 250 U/hour	6 hours
40 to 49	No	Increase by 150 U/hour	6 hours
50 to 59	No	Increase by 100 U/hour	6 hours
60 to 90	No	No change	Next morning
91 to 100	No	Decrease by 100 U/hour	6 hours
101 to 120	No	Decrease by 150 U/hour	6 hours
>120	No	Decrease by 250 U/hour	6 hours

Heparin_nomogram_for_stroke.htm

No bolus is administered in patients with acute stroke.

Data from: Toth C, Voll C. Validation of a weight-based nomogram for the use of intravenous heparin in transient ischemic attack or stroke. Stroke 2002; 33:670.

Graphic 53377 Version 2.0

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Heparin-adjusted nomogram for stroke