Drugs that may affect fracture healing

Medication class	Examples	Purported effect
Chemotherapy	Doxorubicin Cyclophosphamide Adriamycin Methotrexate	Decreased callus formation
Glucocorticoids	Dexamethasone Prednisone Methylprednisolone	Evidence is inconsistent; may decrease bone mineralization
Antibiotics	Fluoroquinolones (eg, Levofloxacin) Gentamicin Tetracycline	Fluoroquinolones have adverse effects upon cartilage regrowth and bone healing. Evidence concerning other antibiotics is inconsistent.
NSAIDs	Multiple nonspecific and COX-2 inhibitors	Animal studies suggest decreased healing; human studies are inconsistent

Medication_effects_on_fracture_healing.htm

Graphic 53621 Version 1.0

آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟