Version June 2024
| Symptoms |
| Diarrhea |
| Frequent loose bowel movements without associated rectal irritation |
| Proctitis |
| Rectal irritation or urgency, and the presence of mucous or blood in the stool, with or without frequent or sometimes loose bowel movements |
| Cystitis |
| Irritative bladder symptoms such as frequent dysuria; hematuria may or may not be a part of the clinical picture |
| Grades |
| Grade 0 |
| No symptoms |
| Grade 1 |
| Minor symptoms requiring no treatment |
| Grade 2 |
| Symptoms that respond to simple outpatient management and do not affect lifestyle |
| Grade 3 |
| Distressing symptoms affecting lifestyle; may necessitate hospital admission or minor surgical intervention (eg, urethral dilation) |
| Grade 4 |
| Major surgical intervention or long stay in the hospital necessary (eg, laparotomy, colostomy, or cystectomy) |
| Grade 5 |
| Fatal complications |
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