Survival benefit in repeat metastasectomy is dependent upon thoracic control of disease with increasing number of metastasectomies.
Reference:
Jaklitsch MT, Mery CM, Lukanich JM, et al. Sequential thoracic metastasectomy prolongs survival by re-establishing local control within the chest. J Thorac Cardiovasc Surg 2001; 121:657.
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