Clinical and biological features of CD3-negative NK-LGL leukemia

Clinical features
Splenomegaly	90 percent
Hepatomegaly	60 percent
Lymphadenopathy	27 percent
Biologic features
Marrow infiltration	100 percent
Neutropenia	50 percent
Severe neutropenia (ANC <500/µL)	18 percent
Anemia	100 percent
Thrombocytopenia	75 percent
Hyperlymphocytosis (>10,000/µL)	70 percent
Rarely reported
Gastrointestinal infiltration
Central nervous system involvement
Ascites
Idiopathic thrombocytopenic purpura
Disseminated intravascular coagulation

Features_of_NK_LGL.htm

Reproduced by permission from Cancer Control: Journal of the Moffitt Cancer Center. Lamy, T, Loughran, TP Jr. Large granular lymphocyte leukemia. Cancer Control 1998; 5:25.

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خرید پکیج

Clinical and biological features of CD3-negative NK-LGL leukemia