Immunocytochemical differential diagnosis of Merkel cell carcinoma

Tumour	CK20	CK7	NSE	NFP	S100	LCA	CD99	TTF1
Merkel cell carcinoma	+	-	+	+	-	-	Rarely + (cytoplasmic)	_
Small cell carcinoma	-	+	+	+/-	-	-	Rarely + (cytoplasmic)	+
Lymphoma	-	-	-	-	-	+	-	-
Primitive neuroectodermal tumour	-	-	+	Rarely +	-	-	+ (membranous)	-
Small-cell melanoma	-	-	+	-	+	-	-	-

IHC_stain_Merkel_cell_carci.htm

CK20: cytokeratin 20; CK7: cytokeratin 7; NSE: neuron-specific enolase; NFP: neurofilament protein; S100: S100 protein; LCA: leucocyte common antigen; CD99: cluster-of-differentiation antigen 99; TTF1: thyroid transcription factor 1; +: positive stain; -: negative stain.

Graphic 54954 Version 2.0

خرید پکیج

Immunocytochemical differential diagnosis of Merkel cell carcinoma