Electron micrograph showing membranous nephropathy

Electron micrograph shows stage II membranous nephropathy. Electron-dense deposits (D) are present in the subepithelial space across the glomerular basement membrane (GBM) and under the epithelial cells (Ep). New basement membrane is growing between the deposits, leading to a spike appearance on silver stain.

Electron micrograph of a normal glomerular capillary loop showing the fenestrated endothelial cell (Endo), the glomerular basement membrane (GBM), and the epithelial cells with its interdigitating foot processes (arrow). The GBM is thin, and no electron-dense deposits are present. Two normal platelets are seen in the capillary lumen.