| Hyperthermia | Hypothermia |
| Increased heat production | - Opioids
- Sedative-hypnotics
- Benzodiazepines
- Barbiturates
- Alcohols
- Sympatholytics
- Beta blockers
- ClonidineText
- Alpha-adrenergic antagonists
- Hypoglycemic agents
- Antipsychotics
- General anesthetic agents
- Carbon monoxide
- Drugs that cause flaccid coma
|
- Muscular hyperactivity/rigidity
- Sympathomimetics
- Cocaine
- Amphetamines
- Phenylpropanolamine
- Ephedrine
- Cathinones
- Anticholinergics
- Drug withdrawal states
- Lithium
- Central hallucinogens
- Phencyclidine
- Lysergic acid diethylamide (LSD)
- Designer amphetamines (MDMA, MDEA)
- Synthetic cannabinoids
- Drugs causing recurrent seizures
- Isoniazid
- Theophylline
- Phenethylamines
- Strychnine
- Neuroleptic malignant syndrome
- Serotonin syndrome
- MAO inhibitors
- Malignant hyperthermia
|
| Impaired heat dissipation |
- Impaired sweating
- Anticholinergic agents
- Antihistamines
- Phenothiazines
- Tricyclic antidepressants
|
| Increased metabolic rate |
- Uncoupled oxidative phosphorylation
- Salicylates
- Dinitrophenol, pentachlorophenol
- Thyroid hormone
|
