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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد

Antimicrobial agents that may induce Clostridioides difficile diarrhea and colitis

Antimicrobial agents that may induce Clostridioides difficile diarrhea and colitis
Frequently associated Occasionally associated Rarely associated
  • Fluoroquinolones
  • Clindamycin
  • Penicillins and combinations (broad spectrum)
  • Cephalosporins (2nd/3rd/4th/5th generation)
  • Carbapenems
  • Macrolides
  • Penicillins (narrow spectrum)
  • Cephalosporins (1st generation)*
  • Trimethoprim-sulfamethoxazole
  • Sulfonamides
  • Nitrofurantoin
  • Aminoglycosides
  • Tetracyclines
  • Tigecycline
  • Chloramphenicol
  • Metronidazole
  • Vancomycin
* Use of 1 to 2 doses of a first-generation cephalosporin for surgical antibiotic prophylaxis does not confer significant risk for C. difficile infection.
References:
  1. McDonald LC, Gerding DN, Johnson S, et al. Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clin Infect Dis 2018; 66:987.
  2. Slimings C, Riley TV. Antibiotics and healthcare facility-associated Clostridioides difficile infection: systematic review and meta-analysis: 2020 update. J Antimicrob Chemother 2021:dkab091.
  3. Vardakas KZ, Trigkidis KK, Boukouvala E, Falagas ME. Clostridium difficile infection following systemic antibiotic administration in randomised controlled trials: A systematic review and meta-analysis. Int J Antimicrob Agents 2016; 48:1.
  4. Ge IY, Fevrier HB, Conell C, et al. Reducing risk of Clostridium difficile infection and overall use of antibiotic in the outpatient treatment of urinary tract infection. Ther Adv Urol 2018; 10:10.
  5. Okafor CM, Clogher P, Olson D, et al. Trends in and risk factors for recurrent Clostridioides difficile infection, New Haven County, Connecticut, USA, 2015-2020. Emerg Infect Dis 2023; 29:877.
  6. Zhang J, Chen L, Gomez-Simmonds A, et al. Antibiotic-specific risk for community-acquired Clostridioides difficile infection in the United States from 2008 to 2020. Antimicrob Agents Chemother 2022; 66:e0112922.
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