ACF: aberrant crypt foci;
APC: adenomatous polyposis coli gene;
DCC: deleted in colon cancer gene;
LOH: loss of heterozygosity;
MMR: DNA mismatch repair enzyme.
Adapted from: Lynch, JP, Hoops, TC. The genetic pathogenesis of colorectal cancer. Hematol Oncol Clin North Am 2002; 16:775.
