Version June 2024
| Increased |
| Collagen I and III mRNA and protein production |
| Proteoglycan synthesis |
| Fibronectin synthesis |
| Prolyl and lysyl hydroxylase enzyme activity |
| PDGF receptor expression |
| Production of IL-1 and IL-6 |
| Serum independent proliferation |
| Surface expression and shedding of ICAM-1 |
| Collagenase secretion |
| Suceptibility to anti-Fas induced apoptosis |
| Reduced |
| Collagen I mRNA downregulation in collagen gel matrix culture |
| Collagenase production |
| Proliferative response to recombinant EGF, endothelin-1 |
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