Study drug administration during PCI

	Time since last injection(s)
	≤6 hours		>6 hours
	Last injection Double (fonda/placebo + enox/placebo)	Last injection Single (enox/placebo only)	Last injection Double or single
With GP IIb/IIIa	No study drug	Fonda/placebo 2.5 mg IV	Fonda/placebo 2.5 mg IV + UFH/placebo 0.013 mL/kg IV (65 units/kg)
Without GP IIb/IIIa	Fonda/placebo 2.5 mg IV	Fonda/placebo 5.0 mg IV	Fonda/placebo 5.0 mg IV + UFH/placebo 0.02 mL/kg IV (100 units/kg)

GP: glycoprotein; IV: intravenous; UFH: unfractionated heparin.

Reproduced with permission from: The Fifth Organization to Assess Strategies in Acute Ischemic Syndromes Investigators. Comparison of Fondaparinux and Enoxaparin in Acute Coronary Syndromes. N Engl J Med 2006; 354(14):464. Copyright © 2006 Dr. Salim Yusuf.

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Study drug administration during PCI