Detection rate and false-positive rate for Down syndrome screening tests: First and Second Trimester Evaluation of Risk Trial (FASTER) and Serum, Urine and Ultrasound Screening Study (SURUSS)

Test	FASTER*		SURUSS^¶
Test	Detection rate, percent	FPR, percent	Detection rate, percent	FPR, percent	Procedure related losses per 100,000 women screened
Full integrated	85	0.8	85	0.9	6
Full integrated	95	5	90	2.1	15
Serum integrated	85	4.4	85	3.9	28
Serum integrated	95	17	90	7.4	53
Combined	85	4.8	85	4.3	35
Combined	95	21	90	8.4	60
Quadruple	85	7.3	85	6.2	45
Quadruple	95	22	90	10.6	76

FPR: false positive rate.
* For FASTER, the first trimester combined test or first trimester component of the integrated test was done at 12 completed weeks of gestation.
¶ For SURUSS, the first trimester combined test or first trimester component of the integrated test was done at 11 completed weeks of gestation.

Adapted from: Wald NJ, Rodeck C, Hackshaw AK, et al. Health Technol Assess 2003; 7:1.

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خرید پکیج

Detection rate and false-positive rate for Down syndrome screening tests: First and Second Trimester Evaluation of Risk Trial (FASTER) and Serum, Urine and Ultrasound Screening Study (SURUSS)