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تعداد آیتم قابل مشاهده باقیمانده: 4

Content of human neutrophil granules

Content of human neutrophil granules
Granule Azurophil Specific Gelatinase Secretory vesicles
Marker enzyme Myeloperoxidase Lactoferrin Gelantinase Alkaline phosphatase
Membrane CD63 granulophysin CD15, CD66, CD67 CD11b/CD18 CD10, CD13, CD45, CD35 (CR1)
CD68 CD11b/CD18   CD11b/CD18
Oxidase receptors    Cytochrome b Cytochrome b  Cytochrome b 
Rap1A Rap1A Rap1A
fMLP R fMLP R fMLP R
C3bi R C3bi R CR1
Fibronectin R   C3bi R (CR3)
Laminin R CR4
Vitronectin R C1q R
  Fc-gamma-RIII (CD16)
Plasminogen activator R
Signal transduction Thrombospondin R Diacylglycerol deacylating enzyme Decay-accelerating factor  
Gi2 protein subunit
Others Nb antigen      
9 kd and 155 kd proteins
Matrix
Microbicidal Myeloperoxidase Lactoferrin Lysozyme            
Nitric oxide synthase Lysozyme           
Lysozyme          
BPI protein
Defensins
Serprocidins
Elastase
Cathepsin G
Proteinase 3
Azurocidin
(CAP37)
Hydrolases Acid beta glycero-phosphatase alpha Gelatinase Gelatinase       
Mannosidase beta Collagenase Acetyltransferase
Glucuronidase beta Histaminase  
   
Glycerophosphatase Heparanase
N-acetyl-beta glucosaminidase NGAL
Sialidase Sialidase
Other Acid mucopolysaccharide Beta-2 microglobulin Beta-2 microglobulin Plasma proteins
Heparin-binding protein Plasminogen activator     
  Vitamin B12 binding protein
CD: cluster of differentiation; CR: complement receptor; Rap: Ras-related protein; fMLP: formyl-Methionyl-Leucyl-Phenylalanine; R: receptor; C3bi: complement protein fragment 3bi; C1q: complement 1 subcomponent q; Fc-gamma-RIII: low affinity receptor for the crystallizable fragment of immunoglobulin G; Gi2: guanosine nucleotide-binding regulatory protein i2; Nb: Nippostrongylus brasiliensis; kd: kilodalton; BPI: bactericidal/permeability-increasing; CAP37: cationic antimicrobial protein-37; NGAL: neutrophil gelatinase-associated lipocalin.
Adapted from Borregaard N, Kledsen L, Lollike K, Sengelov H. Granules and secretory vesicles of the human neutrophil. Clin Exp Immunol 1995; 101:6.
Graphic 57400 Version 5.0

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