Treatment of Paget disease of the breast with surgery alone

Study	N	Presentation	Treatment	Local recurrence	Median F/U (mos)
Polgár 2002^[1]	33	No mass (30)	Cone excision only	11 (33%)	72
		Mass (3)
Dixon 1991^[2]	37	No mass	Simple mastectomy	2 (5%)	40
	10	No mass	Nipple-areolar resection + resection underlying breast tissue/calcifications	4 (40%)	56
		Calcifications adjacent to nipple on mammogram
Lagios 1984^[3]	5	No mass	Nipple-areolar resection (n = 4)	0 (0%)	50
		Normal mammogram	Partial nipple-areolar resection (n = 1)	1 (100%)
Paone 1981^[4]	5	No mass	Nipple-areolar resection	0 (0%)	NR

References:

Polgár C, Orosz Z, Kovács T, Fodor J. Breast-conserving therapy for Paget disease of the nipple: A prospective European Organization for Research and Treatment of Cancer study of 61 patients. Cancer 2002; 94:1904.
Dixon AR, Galea MH, Ellis IO, et al. Paget's disease of the nipple. Br J Surg 1991; 78:722.
Lagios MD, Westdahl PR, Rose MR, Concannon S. Paget's disease of the nipple. Alternative management in cases without or with minimal extent of underlying breast carcinoma. Cancer 1984; 54:545.
Paone JF, Baker RR. Pathogenesis and treatment of Paget's disease of the breast. Cancer 1981; 48:825.

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