Multivariate Cox model and the points assigned to each category of prognostic factors in the new prognostic score system | ||
Characteristics | Point | |
Patient characteristics | ||
Ascites | Yes | 2 |
No | 0 | |
Abdominal pain | Yes | 2 |
No | 0 | |
Weight loss | Yes | 2 |
No | 0 | |
Child-Pugh grade | C | 5 |
B | 2 | |
A | 0 | |
Biochemistry | ||
Serum alkaline phosphatase (ALP), int. unit/L | >200 | 3 |
≤200 | 0 | |
Total bilirubin | >50 int. unit/L (2.9 mg/dL) | 3 |
>33 to ≤50 int. unit/L (1.9 mg/dL to 2.9 mg/dL) | 1 | |
≤33 int unit/L (1.9 mg/dL) | 0 | |
Urea | >8.9 mmol/L (>25 mg/dL) | 2 |
≤8.9 mmol/L (≤25 mg/dL) | 0 | |
Tumor characteristics | ||
Portal vein thrombosis | Yes | 3 |
No | 0 | |
Tumor size | Diffuse | 4 |
>5 cm | 3 | |
≤5 cm | 0 | |
Lung metastases | Yes | 3 |
No | 0 | |
Serum alpha-fetoprotein (AFP), ng/mL | >400 | 4 |
≤400 | 0 | |
Probability of patients surviving at least 3 months estimated by the advanced liver cancer prognostic system score | ||
Prognosis | Score | 3-month survival rate, % |
Good | 0 to 2 | >81 |
3 to 6 | 72 to 80 | |
7 to 8 | 66 to 69 | |
Intermediate | 9 | 63 |
10 to 12 | 51 to 59 | |
13 to14 | 42 to 7 | |
15 | 38 | |
Poor | 16 | 33 |
17 to 19 | 21 to 29 | |
20 to 22 | 10 to 17 | |
≥23 | <10 |
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