Disease | Potential mechanisms |
Atopic diseases | Allergen-specific IgE |
Chronic autoimmune urticaria | Anti-IgE or anti-Fc-epsilon-RI autoantibodies |
Autoimmunity | IgG receptor, complement |
Chronic infections | TLRs, IgG, complement |
Drug allergy | Specific receptors, complement, IgE |
Physical stimuli | Direct mast cell activation |
Neoplasms | Complement, cytokines |
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