Disease states associated with secondary mast cell activation

Disease	Potential mechanisms
Atopic diseases	Allergen-specific IgE
Chronic autoimmune urticaria	Anti-IgE or anti-Fc-epsilon-RI autoantibodies
Autoimmunity	IgG receptor, complement
Chronic infections	TLRs, IgG, complement
Drug allergy	Specific receptors, complement, IgE
Physical stimuli	Direct mast cell activation
Neoplasms	Complement, cytokines

IgE: immunoglobulin E; Fc-epsilon-RI: high affinity receptor for IgE on mast cells; IgG: immunoglobulin G; TLRs: toll-like receptors.

Graphic 57791 Version 7.0

آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟