World Health Organization immunologic classification for established HIV infection

HIV-associated immunodeficiency	Age-related CD4 values
HIV-associated immunodeficiency	<11 months (CD4 percent)	12 to 35 months (CD4 percent)	36 to 59 months (CD4 percent)	>5 years (absolute number per mm³ or CD4 percent)
None or not significant	>35	>30	>25	>500
Mild	30 to 35	25 to 30	20 to 25	350 to 499
Moderate	25 to 29	20 to 24	15 to 19	200 to 349
Severe	<25	<20	<15	<200 or <15%

CD4 cells are expressed as number of cells per mm³ or percentage of total lymphocytes.

Reproduced with permission from: WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-related disease in adults and children. World Health Organization, Geneva, Switzerland, 2007. Copyright © 2007 World Health Organization. Available at: https://apps.who.int/iris/handle/10665/43699.

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World Health Organization immunologic classification for established HIV infection