Version May 2024
| Treatment | Dose – Adults | Dose – Children |
| Calcium | 1000 to 2000 mg elemental calcium daily (total diet + supplement) in divided doses (calcium carbonate or calcium citrate)* | 30 to 75 mg/kg (up to 1000 to 2000 mg) elemental calcium daily (total diet + supplement) in 4 divided doses (calcium glubionate, calcium carbonate, or calcium citrate)* |
| For adults and children, adjust dose as needed to control symptoms and maintain low-normal serum calcium concentration | ||
| Vitamin D | ||
| Initial: 0.25 to 0.5 mcg daily Maintenance: 0.5 to 2 mcg daily | 0.02 to 0.06 mcg/kg/day in 2 equally divided doses (maximum dose 2 mcg/day) |
| Initial: 0.25 mcg daily Maintenance: 0.5 to 1 mcg daily | Insufficient data |
| 0.2 to 1.2 mg daily | |
| For each form of vitamin D above that is employed, adjust dose as needed to control symptoms and maintain low-normal serum calcium concentration | ||
| Hydrochlorothiazide (if required to control hypercalciuria)Δ | 12.5 to 50 mg daily | 0.5 to 1.5 mg/kg per day (maximum 50 mg daily) |
* Calcium carbonate absorption is better when taken with meals and has the added benefit of binding phosphate intake. Calcium citrate is absorbed when taken with or without meals, and in achlorhydria and patients taking proton pump inhibitors (PPIs) or H2 agonists. However, calcium citrate does not bind phosphate intake. For additional information refer to UpToDate topic reviews of treatment of hypocalcemia and calcium supplementation.
¶ Calcitriol should be administered in divided doses due to its short half-life.
Δ Potassium supplementation or a potassium- and magnesium-sparing diuretic (eg, amiloride 2.5 to 5 mg once or twice a day) may be necessary to offset thiazide-induced hypokalemia.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
