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Thin-cap fibroatheroma with intraplaque hemorrhage

Thin-cap fibroatheroma with intraplaque hemorrhage
Thin-cap fibroatheroma with recent intraplaque hemorrhage.
(1A) Low (x20) and (1B) higher-power (x200) views of a thin-cap fibroatheroma with recent hemorrhage. Note, in 1B there is spillage of erythrocytes from surrounding intraplaque vasa vasorum (arrow).
(2A, 2B) Serial section of the lesion in Panel 1A shows a large pool of extravasated erythrocytes with proximate micro-vessels (arrow). Panel 2B is a high-power view of boxed area in Panel 2A.
Reproduced with permission from: Virmani R, Kolodgie FD, Burke AP, et al. Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage. Arterioscler Thromb Vasc Biol 2005; 25:2054. Copyright © 2005 Lippincott Williams & Wilkins.
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