Version May 2024
| Oral agent | Dose¶ |
| Amoxicillin | 100 mg/kg per day divided in 4 doses; maximum dose 4 g/day |
| Cefadroxil | 100 to 150 mg/kg per day divided in 2 doses; maximum dose 2 g/day |
| Cefixime | 8 mg/kg per day divided in 1 or 2 doses; maximum dose 400 mg/day |
| Cephalexin | 75 to 150 mg/kg per day divided in 3 or 4 doses; maximum dose 4 g/day (some experts recommend up to 6 g/day in 4 divided doses) |
| Clindamycin | 30 to 40Δ mg/kg per day divided in 3 doses; maximum dose 2.7 g/day |
| Cloxacillin◊ | 125 mg/kg per day divided in 4 doses; maximum dose 4 g/day |
| Dicloxacillin§ | 100 mg/kg per day divided in 4 doses; maximum dose 4 g/day |
| Linezolid | <12 years: 30 mg/kg per day divided in 3 doses; maximum dose 1.8 g/day ≥12 years: 600 mg twice per day |
| Penicillin V | 150 mg/kg per day divided in 6 doses; maximum dose 2 g/day |
* Refer to UpToDate topics on treatment of bacterial arthritis and osteomyelitis in children for details regarding indications for particular drugs.
¶ Recommended doses are for patients with normal renal function. Beta-lactam antibiotics administered orally for osteoarticular infections generally are given in higher doses than those used for treatment of other infections and recommended in package inserts.
Δ 40 mg/kg per day is preferred for children ≥3 months.
◊ Cloxacillin is not available in the United States.
§ Dicloxacillin suspension is no longer available.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
