RET mutation-related youngest age of onset of MTC

Age-related progression of hereditary MTC depends on RET genotype
RET genotype of MTC	Youngest age at first diagnosis
918	9 months
630	12 months
634	15 months
609	5 years
620	6 years
804	6 years
611	7 years
618	7 years
790	10 years
891	13 years
912	14 years
533	21 years
791	21 years
768	22 years
666	35 years
649	44 years

MTC: medullary thyroid cancer.

Data from: de Groot JW, Links TP, Plukker JT, et al. RET as a diagnostic and therapeutic target in sporadic and hereditary endocrine tumors. Endocr Rev 2006; 27:535.

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RET mutation-related youngest age of onset of MTC