Potential indicators of success in noninvasive ventilation

Younger age

Lower acuity of illness (APACHE score)

Able to cooperate, better neurologic score

Less air leaking, intact dentition

Moderate hypercarbia (PaCO₂ >45 mmHG, <92 mmHG)

Moderate acidemia (pH <7.35, >7.10)

Improvements in gas exchange as well as heart and respiratory rates within first 2 hours

PaCO₂: partial pressure of carbon dioxide.

Reproduced with permission from: International Concensus Conferences in Intensive Care Medicine: Noninvasive positive pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med 2001; 163:288. Copyright © 2001 American Thoracic Society.

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