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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Biological effects of vasoactive intestinal peptide

Biological effects of vasoactive intestinal peptide
1. Cardiovascular system
Vasodilation
Peripheral
Splanchnic
Coronary
Extracranial
Cerebral
Pulmonary
Genital
Chronotropic effect
Inotropic effect
2. Digestive system
Esophagus
Relaxation of lower sphincter
Contraction in the body
Stomach
Relaxation of antral smooth muscle
Relaxation of fundic smooth muscle
Relaxation of oluscularis mucosae
Small intestine
Relaxation followed by contractions of circular muscle
Contraction of longitudinal muscle
Stimulation or water and ion secretion
Stimulation or Brunner's gland secretion
Regulation of epithelial tight junction proteins
Large intestine
Relaxation of smooth muscle
Water and chloride secretion
Gallbladder
Relaxation of smooth muscle
Inhibition of fluid and NaCl absorption
Liver
Stimulation or biliary secretion
Pancreas
Stimulation of water and HCO3-secretion
3. Endocrine function and metabolism
Metabolism
Lipolysis
Glycogenolysis
Adrenal gland
Stimulation of adrenal steroidogenesis
Kidney
Stimulation of renin secretion
Pancreas
Release of insulin, glucagon, somatostatin, and pancreatic polypeptide
Pituitary/hypothalamus
Release of prolactin, oxytocin, and vasopressin
Thyroid
Stimulation of hormone secretion
4. Urogenital system
Inhibition or myoelectrical and smooth muscle activity
Potential of electrically induced and pilocarpine-induced prostatic secretion
5. Respiratory system
Bronchodilation
Stimulation of submucosal gland secretion
6. Central nervous system
Excitation of cerebral cortical and spinal cord neurons
Hyperthermia
Stimulation or glycogenolysis and of glucose utilization
Hypnogenic and antidipsogenic effects
7. Immune system
Inhibition of mitogen-induced transformation of T-lymphocytes
Stimulation of Ig synthesis
Inhibition of mast cell histamine release
Inhibition of Th1 immune responses
Promotion of Th2 immune responses
Adapted with permission from: Fahrenkurg J. Pharmacol Toxicol 1993; 72:354. Copyright © 1993 Pharmacology & Toxicology.
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