Malignancies commonly diagnosed in patients perceived to be at high risk for developing tumor lysis syndrome

Malignancy	Pediatric (n = 682)		Adult (n = 387)		Total (n = 1069)
Malignancy	Number	Percent	Number	Percent	Number	Percent
Acute lymphoblastic leukemia	433	63	73	19	506	47
Acute myeloid leukemia	74	11	104	27	178	17
Chronic lymphocytic leukemia	0	0	37	10	37	3.5
Chronic myeloid leukemia	6	0.9	36	9	42	4
Non-Hodgkin's lymphoma	122	18	109	28	231	22
Hodgkin's disease	8	1.2	6	1.6	14	1.3
Multiple myeloma	0	0	15	3.9	15	1.4
Other hematologic malignancies	5	0.7	3	0.7	8	0.7
Solid tumors	34	5	4	1	38	3.6

Malignancies_highrisk_TLS.htm

NOTE: Data represent consecutive patients enrolled onto a compassionate-use trial evaluating the efficacy and safety of rasburicase in patients with cancer who presented with, or were at risk of developing, hyperuricemia.

Reproduced with permission from: Coiffier B, Altman A, Pui CH, et al. Guidelines for the management of pediatric and adult tumor lysis syndrome: an evidence-based review. J Clin Oncol 2008; 26:2767. Copyright ©2008 American Society of Clinical Oncology. All rights reserved.

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Malignancies commonly diagnosed in patients perceived to be at high risk for developing tumor lysis syndrome