Terminology and histology of cervical intraepithelial neoplasia

Terminology regarding cytologic and histologic precancerous changes of the uterine cervix. The corresponding terminology from the previous classification systems is shown. Images of the histologic correlates for each category are also shown.

LAST: lower anogenital squamous terminology; LSIL: low-grade squamous intraepithelial lesions; HSIL: high-grade squamous intraepithelial lesions; CIN: cervical intraepithelial neoplasia.
* CIN 2 that is p16-positive is classified as HSIL. CIN 2 that is p16-negative is classified as LSIL.

References:

Darragh TM, Colgan TJ, Thomas Cox J, et al. The Lower Anogenital Squamous Terminology Standardization project for HPV-associated lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology. Int J Gynecol Pathol 2013; 32:76.
Nayar R, Wilbur DC. The Pap Test and Bethesda 2014: "The reports of my demise have been greatly exaggerated. (after a quotation from Mark Twain)". J Low Genit Tract Dis 2015; 19:175.

Graphic 60116 Version 8.0

خرید پکیج

Terminology and histology of cervical intraepithelial neoplasia