Hypothesized model of frailty and adverse health outcomes

Reproduced with permission from: Walston J, Hadley EC, Ferrucci L, et al. Research Agenda for Frailty in Older Adults: Towards a Better Understanding of Physiology and Etiology. J Am Geriatr Soc 2006; 54:991. Copyright © 2006 Wiley-Blackwell.