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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Evolution of skin lesions after liver transplantation

Evolution of skin lesions after liver transplantation
Dermatologic condition Liver disease Evolution after liver transplantation
Acanthosis nigricans Primary biliary cholangitis Improvement.
Alopecia areata Autoimmune hepatitis Frequently improvement in the 4 to 12 weeks following transplantation. Occasionally, new alopecia spots appear with immunosuppression.
Pressure alopecia Living donor Reported in living donors[1,2].
Azure lunules (blue discoloration of the bases of the fingernails) Wilson disease Discoloration disappears as the metabolic defect is corrected.
Lichen planus

Hepatitis C virus

Primary biliary cholangitis		 Improves after liver transplantation. Chronic graft-versus-host-disease and parakeratosis occurring after liver transplantation may have a lichenoid appearance.
Livedo reticularis Primary hyperoxaluria Improvement; livedo reticularis can appear months after transplantation[3].
Panniculitis Alpha-1 antitrypsin deficiency Improvement; panniculitis has been reported to occur in a patient who acquired a PiZZ phenotype and resolve after transplantation[4].
Photosensitivity Erythropoietic protoporphyria Improvement, but it may take months or even years. Recurrence has been described[5]. Intraoperative protection from phototoxic injury with a filter omitting wavelengths below 470 nm is recommended during liver transplantation[6].
Vasculitis Hepatitis C with cryoglobulinemia May worsen after transplantation as the viremia increases. Antiviral therapy may be beneficial[7].
Raynaud phenomenon Primary biliary cholangitis Improvement.
Vitiligo Autoimmune hepatitis Improvement; vitiligo occurring after transplantation due to the destruction of melanocytes by donor-derived immune reaction has been reported[8].
Xanthomas and xanthelasmas Chronic cholestatic diseases, such as primary biliary cholangitis, Alagille syndrome, familial hypercholesterolemia Improvement[9].
References:
  1. Tomioka T, Hayashida M, Hanaoka K. Pressure alopecia in living donors for liver transplantation. Can J Anaesth 2004; 51:186.
  2. Khalaf H, Negmi H, Hassan G, Al-Sebayel M. Postoperative alopecia areata: is pressure-induced ischemia the only cause to blame? Transplant Proc 2004; 36:2158.
  3. Rubenstein MC, Martinelli PT, Bayer-Garner IB, et al. Persistent cutaneous manifestations of hyperoxaluria after combined hepatorenal transplantation. Dermatol Online J 2004; 10:10.
  4. Fernandez-Torres R, Garcia-Silva J, Robles O, et al. Alfa-1-antitrypsin deficiency panniculitis acquired after liver transplant and successfully treated with retransplant. J Am Acad Dermatol 2009; 60:715.
  5. Dowman JK, gunson BK, Mirza DF, et al. UK experience of liver transplantation for erythropoietic protoporphyria. J Inherit Metab Dis 2011; 34:539.
  6. Wahlin S, Srikanthan N, Hamre B, et al. Protection from phototoxic injury during surgery and endoscopy in erythropoietic protoporphyria. Liver Transpl 2008; 14:1340.
  7. Francesca Donata M, Banfi G, Cresseri D, et al. Antiviral therapy of symptomatic HCV-mixed 
cryoglobulinemia after liver transplant: Case 
report and literature review. Int J Artif Organs. 2013 Feb 28 [Epub ahead of print].
  8. Bradle V, Kemp EH, Dickinson C, et al. Vitiligo following a combined liver-kidney transplant. Nephrol Dial Transplant 2009; 24:686.
  9. Maiorana A, Nobil V, Calandra S, et al. Preemptive liver transplantation in a child with familial hypercholesterolemia. Pediatr Transplant 2011; 15:E25.
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