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Iodine content of some iodine-containing medications and radiographic contrast agents

Iodine content of some iodine-containing medications and radiographic contrast agents
Substance Amount of iodine
Potassium iodides (thyroprotectant and prethyroidectomy agents)
Potassium iodide oral tablet 50 mg iodine per 65 mg potassium iodide tablet; 100 mg iodine per 130 mg potassium iodide tablet
Potassium iodide oral solution 50 mg iodine per mL of 65 mg/mL potassium iodide solution
Potassium iodide oral saturated solution (SSKI) 770 mg iodine per mL (approximately 20 drops) of 1000 mg/mL potassium iodide saturated solution
Potassium iodide and iodine mixture (Lugol solution, Strong iodine solution) Total 127 mg iodine per mL (approximately 20 drops) of 100 mg/mL potassium iodide and 50 mg/mL iodine mixture
Antiarrhythmic drugs
Amiodarone 75 mg iodine per 200 mg amiodarone*
Radiographic preparations
Iodinated contrast agents Significant source of short-term iodine exposure. Typical oral preparations may contain 300 to 480 mg iodine per mL or tablet.
Intravenous preparations 140 to 400 mg/mL
Topical antiseptic agents
Povidone-iodine solution 10% 10 mg iodine per mL solution
Iodine tinctures 2 and 7% 20 mg iodine per mL of 2% tincture; 70 mg iodine per mL of 7% tincture
Cadexomer-iodine dressings, ointment, powder, paste 9 mg iodine per gram of cadexomer-iodine ointment, powder or paste
Iodoquinol cream 1% 6.4 mg iodine per gram of 1% cream (preparation may include 1 or 2% hydrocortisone)
Clioquinol cream 3% 12 mg iodine per gram of 3% cream
Amebicidal
Iodoquinol (Yodoxin, Diodoquin) 134 mg iodine per 210 mg iodoquinol oral capsule; 415 mg iodine per 650 mg iodoquinol oral capsule
Douches
Povidone-iodine 10 mg iodine per mL solution
Iodine containing expectorants
Iodinated glycerol, calcium iodide Iodine has largely been discontinued as an ingredient of expectorants due to safety concerns. Typical preparations formerly available in the United States contained approximately 6 to 25 mg iodine per mL.
Kelp or seaweed containing supplements
Oral kelp (wrack, bladderwrack) Up to 6 mg of iodine may be contained in a 600 mg serving of kelpΔ
Cellasene (anti-cellulite supplement) 720 mcg of iodine per serving
* Approximately 10% is released as free inorganic iodine. Accumulation of amiodarone in body tissue results in a prolonged iodine exposure half-life (months or more) after discontinuation.
¶ Clioquinol cream is not available as a single ingredient or combination product in the United States. It is available in combinations with flumethasone as a topical cream and as otic in Canada.
Δ Iodine content is variable due to variability in source kelp and preparation.
Graphic 60901 Version 6.0

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