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Criteria for diagnosis of nonmalignant lung disease related to asbestos

Criteria for diagnosis of nonmalignant lung disease related to asbestos
1986 Guidelines
Chest film (irregular opacities)
Pathology (College of American Pathologists)
Consistent time interval
Occupational and environmental history
Asbestos bodies or fibers
2004 Guidelines
Evidence of structural change, as demonstrated by one or more of the following:
Imaging methods
Histology (College of American Pathologists)
Evidence of plausible causation, as demonstrated by one or more of the following:
Occupational and environmental history of exposure (with plausible latency)
Markers of exposure (eg, plaques)
Recovery of asbestos bodies in lung tissue
Comparison and notes
Demonstrates the existence of a structural lesion consistent with the effects of asbestos. The criteria outlined in the 1986 were most explicit for asbestosis.
Chest film, HRCT, and possibly future methods based on imaging. The 1986 guidelines specified ILO classification 1/1.
Criteria for identifying asbestosis on microscopic examination of tissue are unchanged.
Evidence of plausible causation implies that the temporal relationship, including latency, is plausible.
The 2004 guidelines are not limited to lung tissue, consider the role of BAL to be established, and deemphasize fibers because they are difficult to detect and a systematic analysis for asbestos fibers is not generally available.
Dx_asbestos_disease_A.htm
Am J Respir Crit Care Med vol 170 pp 692, 2004; www.atsjournals.org.
Graphic 61308 Version 1.0

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