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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Evaluation of conditions that co-occur with asthma

Evaluation of conditions that co-occur with asthma
Diagnosis Clinical features Testing
Allergic bronchopulmonary aspergillosis

History of asthma or cystic fibrosis

Cough productive of phlegm with "bronchial casts"

Eosinophilia

IgE: >1000 IU/mL

Skin test: positive for aspergillus

Aspergillus IgG: 2 fold elevation

HRCT: mucous plugging, proximal bronchiectasis

Cardiac disease Crackles or wheezes

B type natriuretic peptide: elevated

Chest radiograph: increased interstitial opacities, ±cardiomegaly

Echocardiogram

Chronic eosinophilic pneumonia

Asthma predates or develops in over 50 percent of patients

Fever, weight loss, and night sweats are common

Peripheral blood: ±eosinophilia

Chest radiograph: bilateral peripheral opacities

BAL: eosinophilia >40 pecent

Eosinophilic granulomatosis polyangiitis (Churg Strauss)

Cutaneous, neurologic, or other evidence vasculitis

Paranasal sinus disease

ANCA: positive in 50 percent of patients

Eosinophilia: >10 percent

Chest radiograph: patchy opacities

Biopsy: granulomatous angiitis

COPD Smoking history PFTs: irreversible airflow obstruction and sometimes low DLCO
GERD May complain of chest tightness/restriction or nocturnal choking

Response to empiric treatment with PPI

pH probe monitoring: acid reflux

Spirometry normal, methacholine negative*

Obstructive sleep apnea

Daytime hypersomnolence

Nocturnal choking

Snoring

Polysomnogram: elevated apnea hypopnea index
Tobacco smoke exposure History  
Inducible laryngeal obstruction (vocal cord dysfunction)

Hoarseness/stridor (can be inspiratory and/or expiratory)

Symptoms provoked by exercise

Flow volume loop: slowing on inspiration

Direct laryngoscopy (possibly during exercise or methacholine challenge): abnormal cord motion

ANCA: antineutrophil cytoplasmic antibodies; BAL: bronchoalveolar lavage; CTD: connective tissue disease; DLCO: diffusing capacity; GERD: gastroesophageal reflux disease; HRCT: high resolution computed tomography; PFTs: pulmonary function testing; PPI: proton pump inhibitor.
* GERD can also coexist with asthma in which case methacholine challenge would be positive.
Graphic 61331 Version 4.0

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