NCI CTCAE v5.0 pneumonitis

Adverse event	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Pneumonitis	Asymptomatic; clinical or diagnostic observations only; intervention not indicated	Symptomatic; medical intervention indicated; limiting instrumental ADL*	Severe symptoms; limiting self-care ADL*; oxygen indicated	Life-threatening respiratory compromise; urgent intervention indicated (eg, tracheostomy or intubation)	Death

Pneumonitis is characterized by inflammation focally or diffusely affecting the lung parenchyma.

NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events; ADL: activities of daily living.
* Instrumental ADLs include preparing meals, shopping, using the telephone, managing money. Self-care ADLs include bathing, dressing, using the toilet, taking medications.

Reproduced from: Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0, November 2017, National Institutes of Health, National Cancer Institute. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf (Accessed March 27, 2018).

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NCI CTCAE v5.0 pneumonitis