Syndrome | Clinical manifestations | Causes |
Segmental (transection) syndrome | Loss of all sensory modalities, weakness below affected level; bladder dysfunction | Trauma, hemorrhage, epidural abscess, transverse myelitis, epidural metastasis |
Dorsal cord syndrome | Loss of proprioception, vibratory sensation; variable weakness and bladder dysfunction | Tabes dorsalis, Friedreich ataxia, subacute combined degeneration, AIDS myelopathy, epidural metastases, cervical spondylotic myelopathy, multiple sclerosis |
Ventral cord syndrome (anterior spinal artery syndrome) | Loss of pain and temperature sensation, weakness, bladder dysfunction | Spinal cord infarction, disc herniation, radiation myelopathy, HTLV-1 |
Brown Sequard syndrome | Ipsilateral weakness and loss of proprioception; contralateral loss of pain and temperature sensation | Knife or bullet injury, multiple sclerosis |
Central cord syndrome | Segmental loss of pain and temperature, weakness often greater in the arms than legs | Syringomyelia, intramedullary tumor, acute injury in cervical spondylotic myelopathy |
Pure motor syndrome | Weakness without sensory disturbance | Poliomyelitis, amyotrophic lateral sclerosis, HTLV-1, hereditary spastic paraplegia, lathyrism |
Conus medullaris syndrome | Bladder and rectal dysfunction, saddle anesthesia | Disc herniation, trauma, tumors |
Cauda equina syndrome | Asymmetric multiradicular pain, leg weakness, and sensory loss; bladder dysfunction | Disc herniation, arachnoiditis, tumor, lumbar spine stenosis |
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