Early repair in acute osteomyelitis

Light micrograph in acute osteomyelitis of the tibial articular apparatus. The presence of whorls of chondrocytes (arrows) indicates early tissue repair in which multinucleated osteoclasts (dashed arrows) are actively remodeling the subchondral region. Bone (arrowhead) has replaced the mature lamellar structure, and the medullary spaces are largely filled with inflammatory cells and fibrin.