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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Selected contemporary series of cytoreduction surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with malignant peritoneal mesothelioma (MPM)

Selected contemporary series of cytoreduction surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with malignant peritoneal mesothelioma (MPM)
Author, year n Percent optimally cytoreduced* HIPEC agents Overall survival Favorable prognostic factors Preoperative morbidity and mortality
Yan T, 2009 401 46 Cisplatin and Dox; cisplatin, MMC, or both

Median 53 months (range 1 to 235)

Five-year: 47%

Epithelioid subtype

Negative LNs

Optimal CCR

HIPEC
31%/2%
Alexander HR, 2013 211 53 Cisplatin or MMC

Median 38 months

Five-year: 41%

Histologic grade

Optimal CCR

Age <60 y

Cisplatin HIPEC
30%/2.3%
Baratti D, 2013 108 66
(estimated)
Cisplatin and Dox

Median 63 months

Five-year estimated: 50%

Epithelioid subtype

Neg LNs

Low mitotic rate
39%/1.9%
Schaub NP, 2013 104 66 Cisplatin

Median 52 months (range 1 to 81)

Five-year: 46%

Epithelioid subtype

Low PCI

Low pre-op CA-125
N/A
Hommell-Fontaine J, 2013 28 70 Cisplatin and MMC Median 37 months <5% GLUT-1 expression N/A
Magge D, 2014 65 86 MMC (94%)

Median 46 months

Five-year: 39%

Younger age

Low PCI

Optimal CCR

Histologic grade

No post-op sepsis
35%/6%
Shetty S, 2014 44 81 Carboplatin or MMC Five-year: 53% Carboplatin versus MMC -/0%
CCR: Completeness of surgical cytoreduction score; Dox: doxorubicin; LNs: lymph nodes; MMC: mitomycin C; PCI: peritoneal cancer index; HIPEC: heated intraperitoneal chemotherapy.
* CCR score 0 or 1.
Graphic 64317 Version 5.0

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