Accepted and experimental transplantation approaches in thalassemia

HLA-identical sibling transplant; bone marrow as preferred stem cell source	Accepted
HLA-molecularly-matched unrelated donor transplant	Accepted
HLA-identical sibling cord blood transplant	Accepted
HLA-matched unrelated cord blood transplant	Experimental
HLA-mismatched related donor transplant	Experimental
Nonmyeloablative transplant	Experimental

HLA: human leukocyte antigen.

Originally published in Hematology 2010. Angelucci E. Hematopoietic stem cell transplantation in thalassemia. Hematology Am Soc Hematol Educ Program 2010; 2010:456. Copyright © 2010 American Society of Hematology. Updated according to Angelucci E, et al. Hematopoietic stem cell transplantation in thalassemia major and sickle cell disease: Indications and management recommendations from an international expert panel. Haematologica 2014; 99:811.

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Accepted and experimental transplantation approaches in thalassemia