Overall survival in acute myeloid leukemia

This figure illustrates overall survival in adult subjects with acute myeloid leukemia (AML, age range 15 to 86 years, median 52 years), according to the following cytogenetic risk categories: Favorable risk (median survival 7.6 years): t(8;21); inv(16) or t(16;16); del(9q). Intermediate risk (median survival 1.3 years): normal karyotype; -Y; del(5q); loss of 7q; t(9;11); +11; del(11q); abn(12p); +13; del(20q); +21. Adverse risk (median survival 0.5 years): complex karyotype (≥3 abnormalities); inv(3) or t(3;3); t(6;9); t(6;11); -7; +8 (sole abnormality); +8 with one other abnormality other than t(8;21), t(9;11), inv(16), or t(16;16); t(11;19)(q23;p13.1).