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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده: مورد

In vitro activity of antifungals against Scedosporium and Lomentospora spp

In vitro activity of antifungals against Scedosporium and Lomentospora spp
Drug Scedosporium apiospermum Lomentospora prolificans
Amphotericin B – IR[1]
Voriconazole + –
Posaconazole + –
Isavuconazole + –
Terbinafine – –*
Echinocandins – –
Olorofim (formerly F901318) + +
Fosmanogepix or APX001 (formerly E1211) + +

IR: Intrinsic resistance.

* Terbinafine is sometimes used in combination with other antifungal agents for the treatment of L. prolificans infections for possible synergistic effect.
Reference:
  1. Clinical and Laboratory Standards Institute. CLSI supplement M38M51S: Performance Standards for Antifungal Susceptibility Testing of Filamentous Fungi, 3rd ed, Clinical and Laboratory Institute 2022.
Graphic 65426 Version 8.0

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