Coronary artery stents approved in the United States

Name	Manufacturer	Stent material	Drug	Polymer (thickness) and drug-elution kinetics
Bare metal stents
Vision	Abbott Vascular	Cobalt chromium
REBEL	Boston Scientific	Platinum chromium
Integrity	Medtronic	Cobalt chromium
Durable polymer bare metal stents
COBRA	CeloNova Biosciences	Cobalt chromium		Poly(bis [trifluoroethoxy] phosphazene) ≤50 nm
Durable polymer drug-eluting stents currently in use
Xience (Sierra, V, Prime, Xpedition)	Abbott Vascular	Cobalt chromium	Everolimus	PBMA/PVDF-HFP 7.6 micrometers; 80% within four weeks
Promus (Elite, Premier)	Boston Scientific	Platinum chromium	Everolimus	PBMA/PVDF-HFP 7.6 micrometers; 80% within four weeks
Resolute (Onyx, Integrity)	Medtronic	Cobalt chromium	Zotarolimus	Biolynx* 5.6 micrometers; 85% within eight weeks
Bioabsorbable polymer drug-eluting stents currently in use
SYNERGY	Boston Scientific	Platinum chromium	Everolimus	Poly-lactide-co-glycide^¶ 4 micrometers; >95% within 90 days
Orsiro	Biotronik	Cobalt chromium	Sirolimus	BIOlut poly-L-lactide^Δ 7.5 micrometers; >95% within 14 weeks
Previously approved drug-eluting stents
Cypher	Cordis/J&J	Stainless steel	Sirolimus	PEVA/PBMA 12.6 micrometers; >80% within four weeks
Taxus	Boston Scientific	Stainless steel	Paclitaxel	SIBBS 16 micrometers; approximately 10% over two weeks
Taxus Ion	Boston Scientific	Platinum chromium	Paclitaxel	SIBBS 16 micrometers; approximately 10% over two weeks
Endeavor	Medtronic	Cobalt chromium	Zotarolimus	Phosphoryl choline 5.3 micrometers; 95% within two weeks

PBMA: poly(n-butyl methacrylate); PVDF-HFP: poly(vinylidene fluoride-hexafluoropropylene); PEVA: polyethylene-co-vinyl acetate; SIBBS: styrene-b-isobutylene-b-styrene).
* Proprietary polymer.
¶ Biodegradable polymer (absorption time 120 days).
Δ Biodegradable polymer (absorption time 12 to 24 months).

Courtesy of J Dawn Abbott, MD.

Graphic 65603 Version 19.0

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Coronary artery stents approved in the United States