Prevalence of IgE deficiency (<2.5 international units/mL)

Study group	Number of subjects (adults)	Prevalence, percent
Study group	Number of subjects (adults)	Percentage with selective IgE deficiency*	Percentage with IgE + other immunoglobulin deficiencies Deficient immunoglobulins, in decreasing order	Total
Blood donors	500	0.8	1.8 IgG4	2.6
Allergy and Immunology clinic patients	974	3.1	5.0 IgG4, IgG1, IgG2, IgG3	8.1
Rheumatology clinic patients	155	1.3	8.4 IgA2, IgA1, IgG2, IgG4	9.7
Total	1629

Ig: immunoglobulin.
* Normal serum levels of IgG, IgA, IgM, IgA1, IgA2, IgG1, IgG2, IgG3, and IgG4

Courtesy of John K Smith, MD and Guha Krishnaswamy, MD.

Graphic 65822 Version 6.0

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