Simplified schematic overview of the mevalonate pathway, which is distributed at the level of mevalonate kinase in mevalonate kinase deficiency

From: Stoffels M, Simon A. Hyper-IgD syndrome or mevalonate kinase deficiency. Curr Opin Rheumatol 2011; 23:419. DOI: 10.1097/BOR.0b013e328349c3b1. Copyright © 2011. Reproduced with permission from Wolters Kluwer Health. Unauthorized reproduction of this material is prohibited.