Cytoplasmic and mitochondrial distribution of heme synthesis enzymatic steps in the erythroblast

Modified from: Bottomley, SS. Iron overload in sideroblastic and other non- thalassemic anemias. In: Hemochromatosis: Genetics, Pathophysiology, Diagnosis and Treatment. Barton, JC, Edwards, CQ (Eds), Cambridge University Press, Cambridge UK 2000. p.422.