Version July 2025
| Phenotype | |
| Missing hematopoietic growth factor or growth factor receptor | |
| GM-CSF | Normal hematopoiesis and progenitors |
| Progressive accumulation of pulmonary surfactant | |
| G-CSF | Circulating neutrophils 25 percent of normal |
| Progenitors 50 percent of normal | |
| Impaired response to Listeria monocytogenes infection | |
| IL-3/GM-CSF/IL-5 (bc) receptor | Similar to mice lacking GM-CSF |
| Low eosinophils and impaired eosinophil response to N. brasiliensis | |
| Missing transcription factor | |
| PU.1 | Embryonically lethal |
| Absence of granulocytes, monocytes, T and B lymphocytes | |
| C/EBP-alpha | Death soon after birth |
| Absent neutrophils and eosinophils | |
| Impaired glucose metabolism | |
| C/EBP-beta | Defective monocytes |
| Myelodysplasia | |
| C/EBP-epsilon | Early death from opportunistic infection and myelodysplasia |
| Specific granule deficiency and abnormal neutrophil function | |
| AML1 or CBF-beta | Embryonically lethal due to failure of hematopoiesis |
