Actions of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on angiotensin and kinin pathways

Left side of figure: ACE normally converts angiotension I to angiotension II, and ACE inhibitors (ACEIs) inhibit this reaction.
Right side of figure: In the presence of ACEIs, bradykinin is not degraded and binds to bradykinin B₂ receptors.