Version June 2024
| Risk | Stage | Age | MYCN status | DNA ploidy | INPC | Other |
| Low* | 1 | Any | Any | Any | Any | |
| 2a/2b | Any | Not amp | Any | Any | Resection ≥50% | |
| 4s | <365 days | Not amp | DI >1 | FH | Asymptomatic | |
| Intermediate¶ | 2a/2b | 0-12 years | Not amp | Any | Any | Biopsy or resection <50% |
| 3 | <547 days | Not amp | Any | Any | ||
| 3 | ≥547 days - 12 years | Not amp | Any | FH | ||
| 4 | <365 days | Not amp | Any | Any | ||
| 4 | 365 - <547 days | Not amp | DI >1 | FH | ||
| 4s | <365 days | Not amp | Any | Any | Symptomatic | |
| 4s | <365 days | Not amp | DI = 1 | Any | Asymptomatic or symptomatic | |
| 4s | <365 days | Not amp | Any | UH | Asymptomatic or symptomatic | |
| 4s | <365 days | Missing | Missing | Missing | Too sick for biopsy | |
| HighΔ | 2a/2b | Any | Amp | Any | Any | Any degree of resection |
| 3 | Any | Amp | Any | Any | ||
| 3 | ≥547 days | Not amp | Any | UH | ||
| 4 | <365 days | Amp | Any | Any | ||
| 4 | 365 - <547 days | Amp | Any | Any | ||
| 4 | 365 - <547 days | Any | DI = 1 | Any | ||
| 4 | 365 - <547 days | Any | Any | UH | ||
| 4 | ≥547 days | Any | Any | Any | ||
| 4s | <365 days | Amp | Any | Any | Asymptomatic or symptomatic |
INPC: International Neuroblastoma Pathology Classification; FH: favorable histology; UH: unfavorable histology; Amp: amplified; DI: DNA index.
* Low-risk group as defined in Children's Oncology Group trial ANBL00B1.
¶ Intermediate-risk group as defined in Children's Oncology Group trial ANBL0531.
Δ High-risk group as defined in Children's Oncology Group trial ANBL0532.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
