Characteristics of the three nitric oxide synthase (NOS) isoforms

Enzyme designation	Gene designation	Chromosomal location and gene size (kbp)	Cell type where first identified	Regulated by Ca++ flux
Type I, (nNOS)	nos1	12q; >100	Nerve	Yes
Type II, (iNOS)	nos2	17cen-q; 37	Macrophage	No
Type III, (eNOS)	nos3	7q; 21	Vascular endothelium	Yes

Characteristics_of_NOS_isof.htm

NOS: nitric oxide synthetase; eNOS: endothelial cell NOS; iNOS: inducible NOS; nNOS: neuronal cell NOS.

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